| Date | Location | Result | |
| 03/10/22 | Philadelphia, PA (Daskalakis Center) | Hofstra 46, UNCW 45 | Box score |
| 03/05/22 | Wilmington, NC (Trask Coliseum) | Hofstra 67, UNCW 52 | Box score |
| 03/03/22 | Wilmington, NC (Trask Coliseum) | Northeastern 63, UNCW 48 | Box score |
| 02/27/22 | Wilmington, NC | Col. of Charleston 87, UNCW 56 | Box score |
| 02/23/22 | Elon, NC (Schar Center) | Elon 64, UNCW 43 | Box score |
| 02/20/22 | Harrisonburg, VA (AUBC) ) | James Madison 73, UNCW 51 | Box score |
| 02/18/22 | Towson, MD (SECU Arena) | Towson 67, UNCW 51 | Box score |
| 02/16/22 | Williamsburg, VA (Kaplan Arena) | William & Mary 69, UNCW 59 | Box score |
| 02/13/22 | Wilmington, NC (Trask Coliseum) | William & Mary 65, UNCW 63 | Box score |
| 02/11/22 | Wilmington, NC (Trask Coliseum) | Elon 69, UNCW 59 | Box score |
| 02/06/22 | Newark, Del. (Carpenter Center) | Delaware 77, UNCW 62 | Box score |
| 02/04/22 | Philadelphia, Pa. (Daskalakis Center) | Drexel 72, UNCW 39 | Box score |
| 02/01/22 | Hempstead, N.Y.(Mack Sports Complex) | Hofstra 56, UNCW 40 | Box score |
| 01/30/22 | Charleston, S.C. (TD Arena) | Col. of Charleston 87, UNCW 59 | Box score |
| 01/26/22 | Wilmington, N.C. (Trask Coliseum) | Delaware 78, UNCW 69 | Box score |
| 01/23/22 | Wilmington, N.C. (Trask Coliseum) | Towson 72, UNCW 49 | Box score |
| 01/21/22 | Wilmington, N.C. (Trask Coliseum) | James Madison 57, UNCW 56 | Box score |
| 01/09/22 | Wilmington, N.C. (Trask Coliseum) | Drexel 71, UNCW 68 (OT) | Box score |
| 01/05/22 | Boston, Mass. (Cabot Center) | Northeastern 77, UNCW 67 | Box score |
| 12/22/21 | Greensboro, N.C. (Fleming Gym) | UNCW 45, UNC Greensboro 42 | Box score |
| 12/19/21 | Wilmington, N.C. (Trask Coliseum) | East Carolina 79, UNCW 50 | Box score |
| 12/16/21 | Norfolk, Va. (Echols Hall) | Norfolk St. 67, UNCW 56 | Box score |
| 12/01/21 | Rock Hill, S.C. (Winthrop Coliseum) | UNCW 55, Winthrop 48 | Box score |
| 11/27/21 | Wilmington, N.C. (Trask Coliseum) | Radford 51, UNCW 50 | Box score |
| 11/23/21 | Buies Creek, N.C. (Gore Arena) | Campbell 53, UNCW 42 | Box score |
| 11/20/21 | Wilmington, N.C. (Trask Coliseum) | Coastal Carolina 73, UNCW 62 | Box score |
| 11/18/21 | College Park, Md. (XFINITY Center) | Maryland 108, UNCW 66 | Box score |
| 11/14/21 | Durham, N.C. (Cameron Indoor Stadium) | Duke 87, UNCW 45 | Box score |
| 11/10/21 | Wilmington, N.C. (Trask Coliseum) | UNCW 74, Mount Olive 65 | Box score |